Detection of a transient R292K mutation in Influenza A/H3N2 viruses shed for several weeks by an immunocompromised patient

Babady NE, Laplante JM, Tang YW, St George K, et a. Detection of a transient R292K mutation in Influenza A/H3N2 viruses shed for several weeks by an immunocompromised patient. J Clin Microbiol 2015 Jan 14
submited by kickingbird at Jan, 19, 2015 12:4 PM from J Clin Microbiol 2015 Jan 14

We describe the case of an immunocompromised patient, positive for influenza A virus (H3N2), in whom the neuraminidase R292K mutation was transiently detected during oseltamivir treatment. The R292K mutation was identified by direct testing in three of eleven respiratory specimens collected throughout the patient´s illness, but in none of the cultures from those specimens