Increased detection of respiratory syncytial virus, influenza viruses, parainfluenza viruses, and adenoviruses with real-time PCR in patients with respiratory symptoms

VAN DE POL AC, van Loon AM, Wolfs TF, Jansen NJ. Increased detection of respiratory syncytial virus, influenza viruses, parainfluenza viruses, and adenoviruses with real-time PCR in patients with respiratory symptoms. J Clin Microbiol. 2007 May 16
submited by kickingbird at May, 23, 2007 14:34 PM from J Clin Microbiol. 2007 May 16

Respiratory samples (n=267) from hospitalized patients with respiratory symptoms were tested with real-time PCR, viral culture and direct immunofluorescence for RSV, influenza virus, parainfluenza viruses, and adenoviruses. Compared with conventional diagnostics, real-time PCR increased the diagnostic yield for these viruses from 24% to 43% and from 3.5% to 36% in children and adults, respectively.