PAN Wei-qi, etc.,al. Rescue of H5N1 Subtype Influenza Virus which Is Lethal to Mice. Journal of Agricultural Biotechnology
Avian influenza virus is acquiring the ability to cross the species barrier between the avian and mammal. However, the genetic mechanism of this ability has not been well known. Influenza A virus A/Chicken/Guangdong/04(H5N1) which was highly pathogenic to both SPF chicken and BALB/c mice, was successfully rescued by a plasmid-based reverse genetics. The rescued virus R- A/Chicken/Guangdong/04(R-CG) and the wild type A/Chicken/Guangdong/04(W-CG) shared similar biological properties such as in titers of 50% e...
Fulltext can be downloaded at Chinese version of F.I.C
See Also:
Latest articles in those days:
- Highly pathogenic avian influenza as a systemic risk - implications for control and preparedness 17 hours ago
- Multiple introductions and spread of novel reassortant highly pathogenic avian influenza A (H5N1) clade 2.3.4.4b viruses via wild birds, South Korea, 2024-2025 17 hours ago
- [preprint]The mammalian-adaptive PB2-E627K substitution preserves viral fitness of clade 2.3.4.4b H5N1 HPAIV in birds 1 days ago
- Mallard super-shedders of avian influenza exhibit distinct cloacal microbial abundance profiles 1 days ago
- A digitally immune-optimized influenza vaccine broadly neutralizes swine and human H1N1 influenza viruses and protects from heterologous challenge 1 days ago
[Go Top] [Close Window]
