Guang Wu, Shaomin Yan. Prediction of possible mutations in H5N1 hemagglutitins of influenza A virus by means of logistic regression. Comparative Clinical Pathology
The relationship of mutations between 241 H5N1 hemagglutinins of influenza A virus was determined according to their amino acid and RNA codon sequences. Six probability values were calculated for each amino acid in each hemagglutinin. With these six numeric values as independents and the probability of mutation occurrence as dependent, a logistic regression was used to model 753 point mutations from the 241 hemagglutinins to derive population estimates. Thereafter, the future mutation positions in H5N1 hemagglutinin were predicted. Finally, the would-be-mutated amino acids in H5N1 hemagglutinin were predicted by means of translation probabilities between RNA codons and mutated amino acids.
See Also:
Latest articles in those days:
- Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Dairy Farm Worker 9 hours ago
- [preprint] Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle 1 days ago
- Modelling the transmission dynamics of H9N2 avian influenza viruses in a live bird market 1 days ago
- CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age 4 days ago
- Surveillance for highly pathogenic avian influenza A (H5N1) in a raptor rehabilitation center-2022 4 days ago
[Go Top] [Close Window]