Yunoki M, Kubota-Koketsu R, Shioda T. Decline in intravenous immunoglobulin titer against influenza virus A/H2N2 derived from donors in Japan. J Med Virol. 2023 Mar 20
Human influenza A/H2N2 can induce a pandemic in the future. This study evaluated the hemagglutination inhibition and neutralizing titers of intravenous immunoglobulin against A/H2N2 viruses, indicating the status of the donor population. In this study, the antibody titers decreased during the study period-2012-2021-suggesting a reduction in the immunity of the studied population.
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