Skarlupka AL, et al. An influenza HA Computationally Optimized Broadly Reactive Antigen elicits antibodies endowed with group-1 heterosubtypic breadth against swine influenza viruses. J Virol. 2020 Jan 29. pii: JVI.02061-19.
Computationally Optimized Broadly Reactive Antigens (COBRA) designed for different influenza virus subtypes (H1N1, H3N2 and H5N1) elicit a subtype-specific broad antibody (Ab) response in na?ve as well as in pre-immune influenza virus animal models (1-9).….
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