List of Abbreviations ARDS Acute Respiratory Distress Syndrome HA Haemagglutinin GAFF General Amber force field MD Molecular Dynamic NA Neuraminidase NAI Neuraminidase Inhibitor PCA Principal Component Analysis ROG Radius of Gyration RIN Residue Interaction Network RMSD Root Mean Square Deviation RMSF Root Mean Square Fluctuations VMD Visual Molecular Dynamics.