Recently, a study in this journal suggested that the 2014 H1N1 pandemic 2009 (H1N1/pdm2009) had gene communication with 2016/2017 H3N2. The influenza A H1N1/pdm2009 virus, a novel swine-derived, triple reassortant virus, was rapidly transmitted between humans and spread to 168 countries, resulting in over 123,000 human deaths globally from March to December 2009. Since then, it has replaced the previous seasonal H1N1 and circulated as a seasonal virus along with the H3N2 virus, posing substantial risks to human populations, creating an opportunity for coinfection and therefore recombination or reassortment between them.