Li X, et al. Rapid Evolution and Gene Communication of H3N2 and H1N1 Influenza A Viruses. J Infect. 2019 Mar 22. pii: S0163-4453(19)30094-5.
?The haplotype network map shows that the 2014 H1N1 strain has gene communication with the 2016/17 H3N2 strain,it may change in the characteristic of the virus by gene communication.
?The genetic evolution rates of H1N1 and H3N2 influenza viruses are fluctuant from 2013 to 2019, it may be related to the subtypes that were prevalent that year.
?From the end of 2018 to the beginning of 2019, the genetic evolution rate of H1N1 influenza virus increased significantly (1.13E-3), indicating that the virus changes rapidly in the short term, triggering viral replication, resistance and transmission changes.
?The genetic evolution rates of H1N1 and H3N2 influenza viruses are fluctuant from 2013 to 2019, it may be related to the subtypes that were prevalent that year.
?From the end of 2018 to the beginning of 2019, the genetic evolution rate of H1N1 influenza virus increased significantly (1.13E-3), indicating that the virus changes rapidly in the short term, triggering viral replication, resistance and transmission changes.
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