Rajao DS, Vincent AL, Perez DR. Adaptation of Human Influenza Viruses to Swine. Front Vet Sci. 2019 Jan 22;5:347
A large diversity of influenza A viruses (IAV) within the H1N1/N2 and H3N2 subtypes circulates in pigs globally, with different lineages predominating in specific regions of the globe. A common characteristic of the ecology of IAV in swine in different regions is the periodic spillover of human seasonal viruses. Such human viruses resulted in sustained transmission in swine in several countries, leading to the establishment of novel IAV lineages in the swine host and contributing to the genetic and antigenic diversity of influenza observed in pigs. In this review we discuss the frequent occurrence of reverse-zoonosis of IAV from humans to pigs that have contributed to the global viral diversity in swine in a continuous manner, describe host-range factors that may be related to the adaptation of these human-origin viruses to pigs, and how these events could affect the swine industry.
See Also:
Latest articles in those days:
- [preprint]A systematic review of laboratory investigations into the pathogenesis of avian influenza viruses in wild avifauna of North America 12 hours ago
- [preprint]Seabird and sea duck mortalities were lower during the second breeding season in eastern Canada following the introduction of Highly Pathogenic Avian Influenza A H5Nx viruses 12 hours ago
- [preprint]Novel introductions of human-origin H3N2 Influenza viruses in Swine, Chile 12 hours ago
- Long term evolution of human seasonal influenza virus A(H3N2) is associated with an increase in polymerase complex activity 13 hours ago
- Humoral correlates of protection against influenza A H3N2 virus infection 13 hours ago
[Go Top] [Close Window]