WONG JY, Wu P, Lau EH, Tsang TK, et al. Real-time estimation of the hospitalization fatality risk of influenza A(H1N1)pdm09 in Hong Kong. Epidemiol Infect. 2016 Jun;144(8):1579-83.
During the early stage of an epidemic, timely and reliable estimation of the severity of infections are important for predicting the impact that the influenza viruses will have in the population. We obtained age-specific deaths and hospitalizations for patients with laboratory-confirmed H1N1pdm09 infections from June 2009 to December 2009 in Hong Kong. We retrospectively obtained the real-time estimates of the hospitalization fatality risk (HFR), using crude estimation or allowing for right-censoring for final status in some patients. Models accounting for right-censoring performed better than models without adjustments. The risk of deaths in hospitalized patients with confirmed H1N1pdm09 increased with age. Reliable estimates of the HFR could be obtained before the peak of the first wave of H1N1pdm09 in young and middle-aged adults but after the peak in the elderly. In the next influenza pandemic, timely estimation of the HFR will contribute to risk assessment and disease control.
See Also:
Latest articles in those days:
- Sequence-based epitope mapping of high pathogenicity avian influenza H5 clade 2.3.4.4b in Latin America 10 hours ago
- Guanylate-binding protein 1 inhibits inflammatory factors produced by H5N1 virus through Its GTPase activity 10 hours ago
- Influenza D Virus Infection in China, 2022-2023 2 days ago
- Evidence of reassortment of avian influenza A (H2) viruses in Brazilian shorebirds 2 days ago
- Epitopes in the HA and NA of H5 and H7 avian influenza viruses that are important for antigenic drift 3 days ago
[Go Top] [Close Window]