One human infection with influenza A(H1N2) variant (v) virus was reported by the Nebraska Department of Health and Human Services.

The patient, who is <18 years of age, initially developed respiratory illness during the week ending April 4, 2026 (Week 13). The patient sought healthcare during the week ending April 18, 2026 (Week 15) with worsening symptoms, was not hospitalized, and has recovered from their illness. An investigation by local and state public health officials did not identify direct or indirect swine contact by the patient. Additional investigation identified that a close contact developed mild respiratory illness on the same day as the case, but no cases of human infection with A(H1N2)v virus associated with this case have been identified.

This is the second human infection with a variant influenza virus reported in the 2025-2026 season, and the first reported in 2026; both have been influenza A(H1N2)v viruses.

When an influenza virus that normally circulates in swine (but not people) is detected in a person, it is called a "variant" influenza virus. Most human infections with variant influenza viruses occur following exposure to swine, but limited, non-sustained, human-to-human transmission has occurred. It is important to note that in most cases, variant influenza viruses have not shown the ability to spread easily and sustainably from person to person.