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Wang M, Di B, Zhou D-H, Zheng B-J, Jing H, Lin Y-P. Food Markets with Live Birds as Source of Avian Influenza. Emerg Infect Dis.2006 Nov edition.  Full Text  
submitted by kickingbird at Oct, 9, 2006 from Emerg Infect Dis.2006 Nov edition (via http://www.cdc.gov/ncidod/EID/vol12no11/06-0675.htm)
Highly pathogenic avian influenza virus (HPAI) H5N1 infected 202 persons worldwide and killed 113 as of April 30, 2006 (1). Most patients were exposed to ill or dead birds or were involved in the slaughter ...

Tellier R.. Review of Aerosol Transmission of Influenza A Virus. Emerg Infect Dis. 2006 Nov edition.  Full Text  
submitted by kickingbird at Oct, 9, 2006 from Emerg Infect Dis. 2006 Nov edition (via http://www.cdc.gov/ncidod/EID/vol12no11/06-0426.htm)
Concerns about the likely occurrence of an influenza pandemic in the near future are increasing. The highly pathogenic strains of influenza A (H5N1) virus circulating in Asia, Europe, and Africa have become ...

Wu G, Yan SM.. Mutation trend of hemagglutinin of influenza A virus: a review from a computational mutation viewpoint. Acta Pharmacol Sin. 2006 May;27(5):513-26.  Abstract  
submitted by kickingbird at Sep, 30, 2006 from Acta Pharmacol Sin. 2006 May;27(5):513-26 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Since 1999 we have developed two computational mutation approaches to analyze the protein primary structure whose methodology and implications were reviewed in 2002. Our first approach is the calculation ...

Chen G-W, Chang S-C, Mok C-K, Lo Y-L, Kung Y-N, Hu. Genomic Signatures of Human versus Avian Influenza A Viruses. Emerg Infect Dis. 2006 Sep.  Abstract  
submitted by kickingbird at Sep, 30, 2006 from Emerg Infect Dis. 2006 Sep (via http://www.cdc.gov/NCIDOD/eid/vol12no09/06-0276.htm)
Position-specific entropy profiles created from scanning 306 human and 95 avian influenza A viral genomes showed that 228 of 4,591 amino acid residues yielded significant differences between these 2 viruses. ...

Reeth KV, Labarque G, Pensaert M.. Serological Profiles after Consecutive Experimental Infections of Pigs with European H1N1, H3N2, and H1N2 Swine Influenza Viruses. Viral Immunol. 2006 Fall;19(3):373-82..  Abstract  
submitted by kickingbird at Sep, 28, 2006 from Viral Immunol. 2006 Fall;19(3):373-82. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Swine influenza viruses (SIVs) of H1N1, H3N2, and H1N2 subtypes, with antigenically different hemagglutinins, are currently cocirculating in pigs in Europe. This study aimed to determine whether the hemagglutination ...

Goni N, Baz M, Ruchansky D, Coppola L, Russi J, Cr. Influenza B viruses isolated in Uruguay during the 2002-2005 seasons: Genetic relations and vaccine strain match. Virus Res. 2006 Sep 18; [Epub ahead of print].  Abstract  
submitted by kickingbird at Sep, 28, 2006 from Virus Res. 2006 Sep 18; [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Monitoring antigenic and genetic variations of circulating influenza viruses is critical for the selection of annual vaccine strains. In order to gain insight into the molecular evolution of Influenza ...

Wang S, Taaffe J, Parker C, Solorzano A, Cao H, Ga. The Hemagglutinin (HA) Proteins from H1 and H3 Serotypes of Influenza A Viruses Require Different Antigen Designs for the Induction of Optimal Protective Antibody Responses as Studied by Codon Optimiz. J Virol. 2006 Sep 20; [Epub ahead of print].  Abstract  
submitted by kickingbird at Sep, 28, 2006 from J Virol. 2006 Sep 20; [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Effective antibody responses provide crucial immunity against influenza (Flu) virus infection. The hemagglutinin (HA) protein is the major target of protective antibody responses induced by viral infection ...

Lipatov AS, Hoffmann E, Salomon R, Yen HL, Webster. Cross-Protectiveness and Immunogenicity of Influenza A/Duck/Singapore/3/97(H5) Vaccines against Infection with A/Vietnam/1203/04(H5N1) Virus in Ferrets. J Infect Dis. 2006 Oct 15;194(8):1040-3. Epub 2006.  Abstract  
submitted by kickingbird at Sep, 28, 2006 from J Infect Dis. 2006 Oct 15;194(8):1040-3. Epub 2006 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Ferrets were immunized with two 7- mu g doses of hemagglutinin from inactivated whole-virus vaccines containing the hemagglutinin gene of A/Duck/Singapore/3/97(H5N3) then inoculated with a lethal dose ...

John C. Kash et al.. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature advance online publication 27 September 200.  Abstract  
submitted by kickingbird at Sep, 28, 2006 from Nature advance online publication 27 September 200 (via http://www.nature.com/nature/journal/vaop/ncurrent/abs/natur)
The influenza pandemic of 1918–19 was responsible for about 50 million deaths worldwide1. Modern histopathological analysis of autopsy samples from human influenza cases from 1918 revealed significant ...

Wu G, Yan S. Determination of mutation trend in hemagglutinins by means of translation probability between RNA codons and mutated amino acids. Protein Pept Lett. 2006;13(6):601-9.  Abstract  
submitted by kickingbird at Sep, 26, 2006 from Protein Pept Lett. 2006;13(6):601-9 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
In this study, we used the 183 translation probabilities between RNA codons and mutated amino acids to construct the theoretical distributions of mutated amino acids in hemagglutinins of influenza A virus. ...

Calvo C, García-García ML, Centeno M, Pérez-Bre?a. Influenza C Virus Infection in Children, Spain. Emerg Infect Dis. 2006 Oct.  Abstract  
submitted by kickingbird at Sep, 23, 2006 from Emerg Infect Dis. 2006 Oct (via http://www.cdc.gov/ncidod/EID/vol12no10/05-1170.htm?s_cid=ei)
To the Editor: Influenza viruses cause serious respiratory illness, particularly in infants <24 months of age (1). Despite serologic studies of French adults that showed an influenza virus seroprevalence ...

Rappole JH, Hubálek Z. Birds and Influenza H5N1 Virus Movement to and within North America. Emerg Infect Dis. 2006 Oct.  Abstract  
submitted by kickingbird at Sep, 23, 2006 from Emerg Infect Dis. 2006 Oct (via http://www.cdc.gov/ncidod/EID/vol12no10/05-1577.htm?s_cid=ei)
Highly pathogenic avian influenza (HPAI) H5N1 expanded considerably during 2005 and early 2006 in both avian host species and geographic distribution. Domestic waterfowl and migratory birds are reservoirs, ...

Chang-Won Lee, etc.,al. Characterization of Highly Pathogenic H5N1 Avian Influenza A Viruses Isolated from South Korea. J Virol. 2005 March; 79(6): 3692–3702..  Abstract  
submitted by kickingbird at Sep, 22, 2006 from J Virol. 2005 March; 79(6): 3692–3702. (via http://www.pubmedcentral.gov/articlerender.fcgi?tool=pmcentr)
An unprecedented outbreak of H5N1 highly pathogenic avian influenza (HPAI) has been reported for poultry in eight different Asian countries, including South Korea, since December 2003. A phylogenetic analysis ...

Guang Wu, Shaomin Yan. Prediction of possible mutations in H5N1 hemagglutitins of influenza A virus by means of logistic regression. Comparative Clinical Pathology.  Abstract  
submitted by kickingbird at Sep, 18, 2006 from Comparative Clinical Pathology (via http://www.springerlink.com/content/223635662073g30u/)
The relationship of mutations between 241 H5N1 hemagglutinins of influenza A virus was determined according to their amino acid and RNA codon sequences. Six probability values were calculated for each ...

JS Brownstein, CJ Wolfe, KD Mandl. Empirical Evidence for the Effect of Airline Travel on Inter-Regional Influenza Spread in the United States. PLoS.  Full Text  
submitted by kickingbird at Sep, 17, 2006 from PLoS (via http://medicine.plosjournals.org/perlserv/?request=get-docum)
Background The influence of air travel on influenza spread has been the subject of numerous investigations using simulation, but very little empirical evidence has been provided. Understanding the role ...

Barr IG, Hurt AC, Iannello P, Tomasov C, Deed N. Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005. Antiviral Res. 2006 Aug 28.  Abstract  
submitted by kickingbird at Sep, 15, 2006 from Antiviral Res. 2006 Aug 28 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
The prevention and control of disease caused by seasonal and potential pandemic influenza viruses is currently managed by the use influenza vaccines and antivirals. The adamantanes (amantadine and rimantadine) ...

Shi D, Yang J, Yang D, Lecluyse EL, Black C, You L. ANTI-INFLUENZA VIRAL PRODRUG OSELTAMIVIR IS ACTIVATED BY CARBOXYLESTERASE HCE1 AND THE ACTIVATION IS INHIBITED BY ANTI-PLATELET AGENT CLOPIDOGREL. J Pharmacol Exp Ther. 2006 Sep 11.  Abstract  
submitted by kickingbird at Sep, 15, 2006 from J Pharmacol Exp Ther. 2006 Sep 11 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Oseltamivir is the main medicine recommended by the World Health Organization in anticipation of next influenza pandemic. This anti-influenza viral agent is an ester prodrug and the anti-viral activity ...

Farrar J, etc.,al. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med. 2006 Sep 10.  Abstract  
submitted by kickingbird at Sep, 15, 2006 from Nat Med. 2006 Sep 10 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Avian influenza A (H5N1) viruses cause severe disease in humans, but the basis for their virulence remains unclear. In vitro and animal studies indicate that high and disseminated viral replication is ...

Callison SA, Hilt DA, Boynton TO, Sample BF, Robis. Development and evaluation of a real-time Taqman RT-PCR assay for the detection of infectious bronchitis virus from infected chickens. J Virol Methods. 2006 Aug 24.  Abstract  
submitted by kickingbird at Sep, 10, 2006 from J Virol Methods. 2006 Aug 24 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
It is important to rapidly differentiate infectious bronchitis virus (IBV) from disease agents like highly pathogenic avian influenza virus and exotic Newcastle disease virus, which can be extremely similar ...

Kalbfuss B, Wolff M, Morenweiser R, Reichl U.. Purification of cell culture-derived human influenza A virus by size-exclusion and anion-exchange chromatography. Biotechnol Bioeng. 2006 Aug 25;.  Abstract  
submitted by kickingbird at Sep, 10, 2006 from Biotechnol Bioeng. 2006 Aug 25; (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
A process comprising of size-exclusion (SEC) and anion-exchange chromatography (AEC) was investigated for downstream processing of cell culture-derived influenza A virus. Human influenza virus A/PR/8/34 ...

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