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2024-3-29 3:20:37
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Trevino C, Bihon S, Pinsky BA.. A Synonymous Change in the Influenza A Neuraminidase Gene Interferes with PCR-based Subtyping and Oseltamivir Resistance Mutation Detection. J Clin Microbiol. 2011 Jun 22..  Abstract  
submitted by kickingbird at Jun, 27, 2011 from J Clin Microbiol. 2011 Jun 22. (via http://www.ncbi.nlm.nih.gov/pubmed/21697334)
Rapid detection of the emergence of oseltamivir-resistant influenza A is critically important for both public health surveillance and the selection of appropriate antiviral therapy.…

FRENSING T, Seitz C, Heynisch B, Patzina C, et al.. Efficient influenza B virus propagation due to deficient interferon-induced antiviral activity in MDCK cells. Vaccine. 2011 Jun 4..  Abstract  
submitted by kickingbird at Jun, 14, 2011 from Vaccine. 2011 Jun 4. (via http://www.ncbi.nlm.nih.gov/pubmed/21651940)
Influenza B virus infections are mainly restricted to humans, which is partially caused by the inability of influenza B virus NS1 protein to counteract the innate immune response of other species. However, ...

WEI HJ, Chang W, Lin SC, Liu WC, et al. Fabrication of influenza virus-like particles using M2 fusion proteins for imaging single viruses and designing vaccines. Vaccine. 2011 Jun 4.  Abstract  
submitted by kickingbird at Jun, 14, 2011 from Vaccine. 2011 Jun 4 (via http://www.ncbi.nlm.nih.gov/pubmed/21651946)
Influenza virus-like particles (VLPs) are noninfectious and the assembly of influenza VLPs depends on the interactions of M1 proteins and/or other viral surface proteins, such as HA, NA, and M2, with the ...

TSAI SM, Chiang YC, Chin LT, Liu HJ, et al.. Novel post-translational modifications of the hemagglutinin and neuraminidase proteins of avian influenza virus expressed by Kluyveromyces lactis. J Virol Methods. 2011 May 27.  Abstract  
submitted by kickingbird at Jun, 14, 2011 from J Virol Methods. 2011 May 27 (via http://www.ncbi.nlm.nih.gov/pubmed/21640140)
Avian influenza virus (AIV) is an enveloped virus with segmented RNA that belongs to the Orthomyxoviridae. Recently, avian influenza virus isolates have not only posed a significant threat to the poultry ...

WANG M, Qi J, Liu Y, Vavricka CJ, et al. Influenza A virus neuraminidase N5 has an extended 150-cavity. J Virol. 2011 Jun 8..  Abstract  
submitted by kickingbird at Jun, 14, 2011 from J Virol. 2011 Jun 8. (via http://www.ncbi.nlm.nih.gov/pubmed/21653672)
There are 9 serotypes of neuraminidase (NA) from influenza A virus (N1-N9) which are classified into two groups based on primary sequences (group 1 and 2). The structural hallmark of the two groups is ...

Govorkova EA, Marathe BM, Prevost A, Rehg JE, Webs. Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets. Antiviral Res. 2011 May 27.  Abstract  
submitted by kickingbird at Jun, 8, 2011 from Antiviral Res. 2011 May 27 (via http://www.ncbi.nlm.nih.gov/pubmed/21635924)
Pandemic 2009 influenza A (H1N1) virus (H1N1pdm) is different from contemporary seasonal human viruses in that it can cause infection deep in the lungs of critical care patients. Here we establish a mammalian ...

SPESOCK A, Malur M, Hossain MJ, Chen LM, et al. The virulence of 1997 H5N1 influenza viruses in the mouse model is increased by correcting a defect in their NS1 proteins. J Virol. 2011 May 18.  Abstract  
submitted by kickingbird at May, 28, 2011 from J Virol. 2011 May 18 (via http://www.ncbi.nlm.nih.gov/pubmed/21593152)
The NS1 protein of human influenza A viruses binds the 30-kDa subunit of the cleavage and polyadenylation specificity factor (CPSF30), a protein required for 3' end processing of cellular pre-mRNAs, thereby ...

SMITH JH, Nagy T, Driskell E, Brooks P, etc al. Comparative Pathology in Ferrets Infected with H1N1 Influenza A Viruses Isolated from Different Hosts. J Virol. 2011 May 18..  Abstract  
submitted by kickingbird at May, 28, 2011 from J Virol. 2011 May 18. (via http://www.ncbi.nlm.nih.gov/pubmed/21593156)
Virus replication and pulmonary disease pathogenesis in ferrets following intranasal infection with a pandemic influenza strain (A/California/4/09; CA09), a human seasonal influenza H1N1 isolate (A/New ...

HOLMES EC, Ghedin E, Halpin RA, Stockwell TB, et a. Extensive Geographical Mixing of Human H1N1/09 Influenza A Virus in a Single University Community. J Virol. 2011 May 18.  Abstract  
submitted by kickingbird at May, 28, 2011 from J Virol. 2011 May 18 (via http://www.ncbi.nlm.nih.gov/pubmed/21593168)
Despite growing interest in the molecular epidemiology of influenza virus, the pattern of viral spread within individual communities remains poorly understood. To determine the phylogeography of influenza ...

Wakai C, Iwama M, Mizumoto K, Nagata K.. Influenza B virus RNA polymerase recognizes the cap structure less dependently on the methyl residue than influenza A virus polymerase. J Virol. 2011 May 18..  Abstract  
submitted by kickingbird at May, 28, 2011 from J Virol. 2011 May 18. (via http://www.ncbi.nlm.nih.gov/pubmed/21593178)
The cap-dependent endonuclease activity of the influenza virus RNA-dependent RNA polymerase cleaves host mRNAs to produce capped RNA fragments for primers to initiate viral mRNA synthesis. The influenza ...

WARREN-GASH C, Bhaskaran K, Hayward A, Leung GM, e. Circulating influenza virus, climatic factors, and acute myocardial infarction: a time series study in England and wales and Hong Kong.. J Infect Dis. 2011 Jun;203(12):1710-8.  Abstract  
submitted by kickingbird at May, 28, 2011 from J Infect Dis. 2011 Jun;203(12):1710-8 (via http://www.ncbi.nlm.nih.gov/pubmed/21606529)
Background.?Previous studies identifying associations between influenza and acute cardiac events may have been confounded by climatic factors. Differing seasonal patterns of influenza activity in Hong ...

Lee SS, Wong NS.. The clustering and transmission dynamics of pandemic influenza A (H1N1) 2009 cases in Hong Kong. J Infect. 2011 May 7.  Abstract  
submitted by kickingbird at May, 28, 2011 from J Infect. 2011 May 7 (via http://www.ncbi.nlm.nih.gov/pubmed/21601284)
Abstract OBJECTIVES: Human influenza A (H1N1) 2009 has caused severe epidemics in many countries, but its dynamics in spatial and temporal contexts have so far been poorly appreciated. METHODS: A ...

TISONCIK JR, Billharz R, Burmakina S, Belisle SE,. The NS1 Protein of Influenza A Virus Suppresses Interferon-Regulated Activation of Antigen Presentation and Immune-Proteasome Pathways. J Gen Virol. 2011 May 18.  Abstract  
submitted by kickingbird at May, 28, 2011 from J Gen Virol. 2011 May 18 (via http://www.ncbi.nlm.nih.gov/pubmed/21593271)
The NS1 protein of influenza virus counters host antiviral defenses primarily by antagonizing the type I interferon response. Both the N-terminal dsRNA binding domain and the C-terminal effector domain ...

ZHOU J, Zou L, Zhang X, Liao J, etc., al. Adamantane- and Oseltamivir-Resistant Seasonal A(H1N1) and Pandemic A(H1N1) 2009 Influenza Viruses in Guangdong, China, During 2008 and 2009. J Clin Microbiol. 2011 May 18..  Abstract  
submitted by kickingbird at May, 28, 2011 from J Clin Microbiol. 2011 May 18. (via http://www.ncbi.nlm.nih.gov/pubmed/21593267)
Adamantane- and oseltamivir-resistance among influenza viruses is a major concern to public health officials. To determine the prevalence of antiviral resistant influenza viruses in Guangdong, China, 244 ...

YAO X, Hamilton RG, Weng NP, Xue QL, et al.. Frailty is associated with impairment of vaccine-induced antibody response and increase in post-vaccination influenza infection in community-dwelling older adults. Vaccine. 2011 May 9.  Abstract  
submitted by kickingbird at May, 23, 2011 from Vaccine. 2011 May 9 (via http://www.ncbi.nlm.nih.gov/pubmed/21565245)
Annual immunization with a trivalent inactivated vaccine (TIV) is considered efficacious for prevention of seasonal influenza in older adults. However, significant controversy exists in the current literature ...

WU C, Zanker D, Valkenburg S, Tan B, et al.. Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals. Proc Natl Acad Sci U S A. 2011 May 11.  Abstract  
submitted by kickingbird at May, 23, 2011 from Proc Natl Acad Sci U S A. 2011 May 11 (via http://www.ncbi.nlm.nih.gov/pubmed/21562214)
Immunodominant T-cell responses are important for virus clearance. However, the identification of immunodominant T-cell peptide + HLA glycoprotein epitopes has been hindered by the extent of HLA polymorphism ...

BUSSEY KA, Desmet EA, Mattiacio JL, Hamilton A, et. PA residues in the 2009 H1N1 pandemic influenza virus enhance avian virus polymerase activity in mammalian cells. J Virol. 2011 May 11..  Abstract  
submitted by kickingbird at May, 23, 2011 from J Virol. 2011 May 11. (via http://www.ncbi.nlm.nih.gov/pubmed/21561908)
The 2009 pandemic influenza virus (pH1N1) is a swine-origin reassortant containing human, avian, and swine influenza genes. We have previously shown that the polymerase complex of the pH1N1 strain A/California/04/2009 ...

Hutchinson E, Orr O, Man Liu S, Engelhardt O, Fodo. Characterisation of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran Binding Protein 5. J Gen Virol. 2011 May 11.  Abstract  
submitted by kickingbird at May, 23, 2011 from J Gen Virol. 2011 May 11 (via http://www.ncbi.nlm.nih.gov/pubmed/21562121)
The influenza A virus RNA polymerase is a heterotrimer, and transcribes and replicates the viral genome in the cell nucleus. Newly synthesised RNA polymerase subunits must therefore be imported into the ...

SIMON P, Holder BP, Bouhy X, Abed Y, et al.. The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant. J Clin Microbiol. 2011 Feb;49(2):715-7. Epub 2010.  Abstract  
submitted by kickingbird at May, 23, 2011 from J Clin Microbiol. 2011 Feb;49(2):715-7. Epub 2010 (via http://www.ncbi.nlm.nih.gov/pubmed/21106781)
Oseltamivir-resistant A/H3N2 influenza isolates with or without the E119V and I222V neuraminidase (NA) mutations were recovered from an immunocompromised patient. Based on plaque size, yield assays, and ...

HAN T, Sui J, Bennett AS, Liddington RC, et al. Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly. Biochem Biophys Res Commun. 2011.  Abstract  
submitted by kickingbird at May, 23, 2011 from Biochem Biophys Res Commun. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/17881439)
Highly pathogenic H5N1 avian influenza viruses pose a debilitating pandemic threat. Thus, understanding mechanisms of antibody-mediated viral inhibition and neutralization escape is critical. Here, a robust ...

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