Marc D.. Influenza virus non-structural protein NS1: interferon-antagonism and beyond. J Gen Virol. 2014 Sep 2. Abstract
submitted by kickingbird at Sep, 7, 2014 from J Gen Virol. 2014 Sep 2 (via http://www.ncbi.nlm.nih.gov/pubmed/25182164)
Most viruses express one or several proteins that counter the anti-viral defences of the host-cell. This is the task of non-structural protein NS1 in influenza viruses. Absent from the viral particle but ... Colvin MT, Andreas LB, Chou JJ, Griffin RG.. Proton Association Constants of His-37 in the Influenza-A M218-60 Dimer-of-Dimers. Biochemistry. 2014 Sep 3. Abstract
submitted by kickingbird at Sep, 7, 2014 from Biochemistry. 2014 Sep 3 (via http://www.ncbi.nlm.nih.gov/pubmed/25184631)
The membrane protein M2 from influenza-A forms a single pass transmembrane helix that assembles in lipid membrane as homo-tetramers whose primary function is to act as a proton gate for viral acidification. ... ZHANG C, Wu Y, Xuan Z, Zhang S, et al. p38MAPK, Rho/ROCK and PKC pathways are involved in influenza-induced cytoskeletal rearrangement and hyperpermeability in PMVEC via phosphorylating ERM. Virus Res. 2014 Aug 19. pii: S0168-1702(14)00305-0. Abstract
submitted by kickingbird at Aug, 30, 2014 from Virus Res. 2014 Aug 19. pii: S0168-1702(14)00305-0 (via http://www.ncbi.nlm.nih.gov/pubmed/25150189)
Severe influenza infections are featured by acute lung injury, a syndrome of pulmonary microvascular leak. A growing number of evidences have shown that the pulmonary microvascular endothelial cells (PMVEC) ... WONG SS, Yoon SW, Zanin M, Song MS, et al. Characterization of an H4N2 influenza virus from Quails with a multibasic motif in the hemagglutinin cleavage site. Virology. 2014 Aug 20;468-470C:72-80. doi: 10.1016. Abstract
submitted by kickingbird at Aug, 30, 2014 from Virology. 2014 Aug 20;468-470C:72-80. doi: 10.1016 (via http://www.ncbi.nlm.nih.gov/pubmed/25151061)
The cleavage motif in the hemagglutinin (HA) protein of highly pathogenic H5 and H7 subtypes of avian influenza viruses is characterized by a peptide insertion or a multibasic cleavage site (MBCS). Here, ... STAUFFER S, Feng Y, Nebioglu F, Heilig R, et al. Stepwise priming by acidic pH and high K+ is required for efficient uncoating of influenza A virus cores after penetration. J Virol. 2014 Aug 27. pii: JVI.01430-14. Abstract
submitted by kickingbird at Aug, 30, 2014 from J Virol. 2014 Aug 27. pii: JVI.01430-14 (via http://www.ncbi.nlm.nih.gov/pubmed/25165113)
Influenza A virus uses the low pH in late endocytic vacuoles as a cue for penetration by membrane fusion. Here, we analyzed the pre-fusion reactions that prepare the core for uncoating after it has been ... POOLE DS, Yu SN, Cai Y, Dinis JM, et al. Influenza A Virus Polymerase Is a Site for Adaptive Changes During Experimental Evolution in Bat Cells. J Virol. 2014 Aug 20. Abstract
submitted by kickingbird at Aug, 25, 2014 from J Virol. 2014 Aug 20 (via http://www.ncbi.nlm.nih.gov/pubmed/25142579)
The recent identification of highly divergent influenza A viruses in bats revealed a new, geographically dispersed viral reservoir. To investigate the molecular mechanisms of host-restricted viral tropism ... MARJUKI H, Mishin VP, Chesnokov AP, Jones J, et al. Characterization of Drug-Resistant Influenza A(H7N9) Variant Viruses Isolated from an Oseltamivir-Treated Patient in Taiwan. J Infect Dis. 2014 Aug 14.. Abstract
submitted by kickingbird at Aug, 25, 2014 from J Infect Dis. 2014 Aug 14. (via http://www.ncbi.nlm.nih.gov/pubmed/25124927)
BACKGROUND:
?Patients contracting influenza A(H7N9) often developed severe disease causing respiratory failure. Neuraminidase (NA) inhibitors (NAIs) are the primary option for treatment, but information ... LORUSSO A, Ciacci-Zanella JR, Zanella EL, Pena L,. Polymorphisms in the hemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine. J Gen Virol. 2014 Aug 15. Abstract
submitted by kickingbird at Aug, 25, 2014 from J Gen Virol. 2014 Aug 15 (via http://www.ncbi.nlm.nih.gov/pubmed/25127710)
Interactions between the viral surface glycoprotein hemagglutinin (HA) and the corresponding receptors on host cells is one important aspect of influenza virus infection. Mutations in the HA have been ... K Wei, etc.,al. Influenza A virus Acquires Enhanced Pathogenicity and Transmissibility After Serial Passages in Swine. 6 August 2014, doi: 10.1128/JVI.01679-14. Abstract
submitted by kickingbird at Aug, 22, 2014 from 6 August 2014, doi: 10.1128/JVI.01679-14 (via http://jvi.asm.org/content/early/2014/07/31/JVI.01679-14.abs)
Genetic and phylogenetic analyses suggest that the pandemic H1N1/2009 virus was derived from well-established swine influenza lineages; however, there is no convincing evidence that the pandemic virus ... Terho Heikkinen, Niina Ikonen, and Thedi Ziegler. Impact of Influenza B Lineage-level Mismatch between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012. Clin Infect Dis. (2014). Abstract
submitted by kickingbird at Aug, 22, 2014 from Clin Infect Dis. (2014) (via http://cid.oxfordjournals.org/content/early/2014/08/19/cid.c)
Background.?Influenza B virus strains in trivalent influenza vaccines are frequently mismatched to the circulating B strains, but the population-level impact of such mismatches is unknown.
We assessed ... He Y, Liu P, Tang S, Chen Y, Pei E, Zhao B, et al. Live Poultry Market Closure and Control of Avian Influenza A(H7N9), Shanghai, China. Emerg Infect Dis. 2014 Sep. Abstract
submitted by kickingbird at Aug, 20, 2014 from Emerg Infect Dis. 2014 Sep (via http://wwwnc.cdc.gov/eid/article/20/9/13-1243_article)
China reported its first human infections with avian influenza A(H7N9) virus in late March 2013 . In the following weeks, 131 human infections were confirmed; 33 occurred in Shanghai. Because infection ... Ku KB, Park EH, Yum J, Kim JA, Oh SK, Seo SH. Highly Pathogenic Avian Influenza A(H5N8) Virus from Waterfowl, South Korea, 2014. Emerg Infect Dis. 2014 Sep. Abstract
submitted by kickingbird at Aug, 20, 2014 from Emerg Infect Dis. 2014 Sep (via http://wwwnc.cdc.gov/eid/article/20/9/14-0390_article)
To date, 18 hemagglutinin (HA) subtypes and 11 neuraminidase (NA) subtypes have been identified in influenza A viruses. Influenza A viruses containing HA subtypes 1–16 circulate in aquatic birds (1,2), ... Lu J, Wu J, Guan D, Yi L, Zeng X, Zou L, et al. Genetic Changes of Reemerged Influenza A(H7N9) Viruses, China. Emerg Infect Dis. 2014 Sep. Abstract
submitted by kickingbird at Aug, 20, 2014 from Emerg Infect Dis. 2014 Sep (via http://wwwnc.cdc.gov/eid/article/20/9/14-0250_article)
From March 30, 2013, through April 8, 2014, a total of 401 human infections with novel avian influenza A (H7N9) virus were reported in China . In the initial wave from February through May 2013, cases ... Yang J, Zhang T, Guo L, Hu Y, Li J, Su H, et al. Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells. Emerg Infect Dis. 2014 Sep. Abstract
submitted by kickingbird at Aug, 20, 2014 from Emerg Infect Dis. 2014 Sep (via http://wwwnc.cdc.gov/eid/article/20/9/14-0257_article)
The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial ... Bowman AS, Nelson SW, Page SL, Nolting JM, Killian. Swine-to-Human Transmission of Influenza A(H3N2) Virus at Agricultural Fairs, Ohio, USA, 2012. Emerg Infect Dis. 2014 Sep. Abstract
submitted by kickingbird at Aug, 20, 2014 from Emerg Infect Dis. 2014 Sep (via http://wwwnc.cdc.gov/eid/article/20/9/13-1082_article)
Agricultural fairs provide an opportunity for bidirectional transmission of influenza A viruses. We sought to determine influenza A virus activity among swine at fairs in the United States. As part of ... Chen Z, Liu H, Lu J, Luo L, Li K, Liu Y, et al. Asymptomatic, Mild, and Severe Influenza A(H7N9) Virus Infection in Humans, Guangzhou, China. Emerg Infect Dis. 2014 Sep. Abstract
submitted by kickingbird at Aug, 20, 2014 from Emerg Infect Dis. 2014 Sep (via http://wwwnc.cdc.gov/eid/article/20/9/14-0424_article)
Targeted surveillance for influenza A(H7N9) identified 21 cases of infection with this virus in Guangzhou, China, during April 1, 2013–March 7, 2014. The spectrum of illness ranged from severe pneumonia ... Goka EA, Vallely PJ, Mutton KJ, Klapper PE.. Mutations associated with severity of the pandemic influenza A(H1N1)pdm09 in humans: a systematic review and meta-analysis of epidemiological evidence. Arch Virol. 2014 Jul 31.. Abstract
submitted by kickingbird at Aug, 3, 2014 from Arch Virol. 2014 Jul 31. (via http://www.ncbi.nlm.nih.gov/pubmed/25078388)
Mutations in the haemagglutinin (HA), non-structural protein 1 (NS1) and polymerase basic protein 2 (PB2) of influenza viruses have been associated with virulence. This study investigated the association ... Gonzalez G, etc.,al. Infection and pathogenesis of canine, equine and human influenza viruses in canine tracheas. Journal of Virology. Abstract
submitted by kickingbird at Jul, 18, 2014 from Journal of Virology (via http://jvi.asm.org/content/early/2014/05/28/JVI.00887-14.abs)
Influenza A viruses (IAVs) can jump species barriers and occasionally cause epidemics, epizootics, pandemics and panzootics. Characterizing the infection dynamics at the target tissues of natural hosts ... Han JK, etc.,al. Persistent detection of avian influenza A/H7N9 virus among poultry in Huzhou City, China, in the summer of 2013. Int J Infect Dis, July 2014. Abstract
submitted by kickingbird at Jul, 18, 2014 from Int J Infect Dis, July 2014 (via http://www.ijidonline.com/article/S1201-9712(14)00057-5/abst)
In eastern China, live poultry markets were successively re-opened in the summer of 2013 following their closure in April 2013. We detected influenza A/H7N9 RNA with positive rates from 4% to 22.2% among ... CHAMBERS BS, Li Y, Hodinka RL, Hensley SE, et al. Recent H3N2 influenza virus clinical isolates rapidly acquire hemagglutinin or neuraminidase mutations when propagated for antigenic analyses. J Virol. 2014 Jul 2. pii: JVI.01077-14.. Abstract
submitted by kickingbird at Jul, 13, 2014 from J Virol. 2014 Jul 2. pii: JVI.01077-14. (via http://www.ncbi.nlm.nih.gov/pubmed/24991002)
Prior to serological testing, influenza viruses are typically propagated in eggs or cell culture. Recent human H3N2 strains bind to cells with low avidity. Here, we isolated 9 primary H3N2 viral isolates ... 7455 items, 20/Page, Page[253/373][|<<] [|<] [251] [252] [253] [254] [255] [256] [257] [258] [259] [260] [>|] [>>|] |
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