This study aimed to estimate the prevalence and seroprevalence of influenza A virus in dogs and cats though a systematic review and meta-analysis was performed following PRISMA guidelines. A total of 79 studies in dogs and 34 in cats were included, encompassing 35,895 dogs and 2882 cats. Subgroup and meta-regression analyses were conducted. The pooled prevalence was 12.04 % (95 % CI: 3.96 - 23.28) in dogs and 1.73 % (95 % CI: 0.00 - 7.10) in cats, while seroprevalence was 12.07 % (95 % CI: 4.4 - 22.49) in dogs and 7.39 % (95 % CI: 3.17 - 13.12) in cats. Significant geographic differences were observed, with higher prevalence in the Americas and Asia compared to Europe. Additionally, prevalence in dogs was higher during spring-summer than in autumn-winter. Meta-regression analysis did not reveal significant associations between prevalence and factors such as symptoms presence, ownership status, or geographic region. However, the high heterogeneity among studies suggests that unaccounted variables, such as detection methods, may contribute to results variability. These findings underscore the epidemiological relevance of canine and feline influenza and highlight the need for ongoing surveillance to monitor geographic and temporal trends.