Sircy LM, Ramstead AG, Gibbs LC, Joshi H, Baessler. Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection. PLoS Pathog. 2024 Sep 16;20(9):e1011639. Abstract submitted by kickingbird at 1 hours ago from PLoS Pathog. 2024 Sep 16;20(9):e1011639 Current influenza vaccine strategies have yet to overcome significant obstacles, including rapid antigenic drift of seasonal influenza viruses, in generating efficacious long-term humoral immunity. Due ... Ahlstrom CA, Torchetti MK, Lenoch J, Beckmen K, Bo. Genomic characterization of highly pathogenic H5 avian influenza viruses from Alaska during 2022 provides evidence for genotype-specific trends of spatiotemporal and interspecies dissemination. Emerg Microbes Infect. 2024 Sep 17:2406291. Abstract submitted by kickingbird at 2 hours ago from Emerg Microbes Infect. 2024 Sep 17:2406291 The ongoing panzootic of highly pathogenic H5 clade 2.3.4.4b avian influenza (HPAI) spread to North America in late 2021, with detections of HPAI viruses in Alaska beginning in April 2022. HPAI viruses ... Yue X, Zhong C, Cao R, Liu S, Qin Z, Liu L, Zhai Y. CircRNA based multivalent neuraminidase vaccine induces broad protection against influenza viruses in mice. NPJ Vaccines. 2024 Sep 16;9(1):170. Abstract submitted by kickingbird at 2 hours ago from NPJ Vaccines. 2024 Sep 16;9(1):170 Developing broad-spectrum influenza vaccines is crucial for influenza control and potential pandemic preparedness. Here, we reported a novel vaccine design utilizing circular RNA (circRNA) as a delivery ... Benito AA, Monteagudo LV, Lázaro-Gaspar S, Mazas-C. Detection and subtyping of influenza A virus in porcine clinical samples from Spain in 2020. Virology. 2024 Sep 8;600:110223. Abstract submitted by kickingbird at 15 hours ago from Virology. 2024 Sep 8;600:110223 A total of 1019 samples collected on 726 Spanish swine farms suffering from outbreaks of respiratory disease were screened for influenza A viruses (IAVs) using a RT-qPCR method. A subset of positive samples ... Root JJ, Porter SM, Lenoch JB, Ellis JW, Bosco-La. Susceptibilities and viral shedding of peridomestic wildlife infected with clade 2.3.4.4b highly pathogenic avian influenza virus (H5N1). Virology. 2024 Sep 5;600:110231. Abstract submitted by kickingbird at 15 hours ago from Virology. 2024 Sep 5;600:110231 We tested the ability of six peridomestic wildlife species to replicate a highly pathogenic (HP) clade 2.3.4.4b AIV (H5N1) isolated in the U.S. during 2022. All tested species replicated and shed virus, ... | |